What new directions are your characters facing? Are they doing so willingly or have they been forced into accepting they've got to go in a direction they have not chosen? What are the consequences?
Can they get back to where they wanted to be and, if so, how do they achieve this? Equally, do they welcome a new direction as the chance to break from everything in their past and start afresh?
How your characters handle change, especially unlooked for change, can reveal a great deal about them so what information are you getting from the way your characters respond to this?